2. Signaling Pathways
  3. TGF-beta/Smad
  4. TGF-β Receptor
  5. GDF15 Isoform
  6. GDF15 Activator

GDF15 Activator

GDF15 Activators (3):

Cat. No. Product Name Effect Purity
  • HY-149406
    AMPK activator 12
    		Activator 99.68%
    AMPK activator 12 (compound 21) is a potent AMPK activator and GDF15 inducer. AMPK activator 12 increases GDF15 protein levels in human hepatic cells.
  • HY-183332
    YXX0248
    		Activator
    YXX0248 is an orally active anti-hypoxic agent. YXX0248 upregulates mRNA expression of FGF21 and GDF15 via activation of the ISR/ATF4 transcriptional axis. YXX0248 exhibits low cytotoxicity. YXX0248 enhances hypoxic survival in mice. YXX0248 can be used for the research of acute mountain sickness and hypoxia-related diseases.
  • HY-183331
    YXX0237
    		Activator
    YXX0237 is an orally active anti-hypoxic agent. YXX0237 upregulates mRNA expression of FGF21 and GDF15 via activation of the ISR/ATF4 transcriptional axis. YXX0237 exhibits low cytotoxicity. YXX0237 enhances hypoxic survival in mice. YXX0237 can be used for the research of acute mountain sickness and hypoxia-related diseases.